I removed the vent. I drilled holes through the side of the vent (the part that is attached to the roof, not the painted cover) for the wires. I was concerned that if I put them through the wire mesh that they would chafe and eventually short to the mesh (you'll see the mesh if you remove the cover).
You may be able to avoid removing the cover by carefully drilling the holes. Of course you should seal the holes after running the wires. I used Proflex RV sealant, making sure it did not drip on the TPO roof (you won't have that concern if your roof is fiberglass).
Also, scrape carefully if you do remove the screws. The paint came up with the Dicor on a couple of my screws when I removed the vent to put in my panel wiring

. The paint does not seem to adhere very well to the plastic.
If I had to do it again I'd try to uncover just enough Dicor to get to the screw's head and try not to disturb the Dicor next to the paint. Fortunately nobody can see it if they aren't on the roof

!
Stewart