On my 2004 Inspire with the 350, the pump is mounted to the back side of the engine front gear cover that drives the injection pump. So it is not an issue AFAIK.
A couple things to consider about the Inspires, you are still riding on a great chassis, same build quality that CC is known for and less bells and whistle stuff to go wrong, that at some point will.
My Lexus weighs right around 5.5k and I live in AZ. While I do slow down on the big grades here, it is not much worse than what I experienced with my Dmax GMC pulling a loaded 28 foot toyhauler. Pretty much same MPG too.
Another upside for the wife and I were the upgrades that the PO had put in, including heated wood floors instead of carpet (kids/dogs), CC factory replaced ceiling LED lighting and flat panel monitors. Not to mention the light ash cabinets and nickel fixtures rather than gold made it feel like a much more modern RV. To each their own, but I detest gold/brass and beveled mirrors... Hey, the '80's called and they want their RV back!
2004 Country Coach 40' Inspire Genoa - Cummins 350
1997 Lexus LX450 (aka Land Cruiser), Air Force One