Gary nailed it with his top three. I can lend some perspective for the horse trailer, as I pull one regularly behind my coach. The main problem I have is dips. The hitch on the coach is SO FAR back behind the rear wheels that even a small dip in the road can cause my trailer's landing gear to hit the ground. Turns and backing are no problem for me, though my coach is almost 10' shorter than the ones you are looking at. The backup camera makes backing relatively easy.
My trailer towing capacity is relatively small, so I had to buy a small, light trailer. I chose a Brenderup 2 horse (The Royal TC
is the one I have) which are not made anymore, but is designed to be able to to be pulled behind light SUVs. I load up my mules and head to the mountains, don't even know it's back there. No rock damage so far, but I wouldn't expect that to be any worse than pulling the trailer behind the dually.