As Bluepill stated, we too use interstates to get to destination and will drop the anchor and explore a 100 mile radius from the campground in the toad. I've always said that if you want to see America, stay off the interstates and I still believe that but I have learned that in my case, RV size may dictate otherwise. On a tree lined 2 lane road I felt uncomfortable driving my 32,000 lb RV/Toad ensemble at the posted 45 mph. The road is narrow, rarely has a sizable shoulder, foliage often hampers vision, and cross intersections may require a fast stop to avoid a mishap. 32,000 pounds can not be stopped as quickly as a car, yet I find myself on a road with rules adequately designed for a car but not for an RV with a towed car. Fuel also becomes an issue. Diesel is always available even on two lane roads. The issue of concern is whether or not the station is located on enough real estate where we can get in and out without leaving paint behind. We have had to pass up many to get to one that could accommodate something our size. As also stated, low overpasses can be an unwanted surprise. While some low overpasses have posted warnings miles in advance, many don't and while I have never had to back up and reroute, I wouldn't find it amusing to do so.
2006 Winnebago Journey 36GSE; 2014 CRV; Blue Ox; SMI AF-1