RANGER REG: YOU can make it a lot easier for our members to help you if you will please add some rig specfic info to your signature (go to profile). The reason that is important is because there IS a difference in fuel filters on the W-22 depending on model year.
To answer your question as best I can:
IF your filter is mounted inside the frame rail, just behind the left (driver's side)rear axle, you only need two open end wrenchs. One to hold, and one to turn. There may be a small gas drip initially, but it is not likely to spray all over if you crack open the connection slowly. Just loosen both ends, remove old, install new, and crank engine to test for leaks.
If you have a newer chassis with the new filter with two fittings on the OUTLET side, I have no experience, but have read it is quite expensive and harder to find. Good luck, ED
2016 EC Aspire 42RBQ / 2014 CR-V