Highway 7 is very scenic, but has some slow lanes etc. Make sure to stop at Ozark Café in Jasper, AR if you go this route.
Another option which is about 94 more miles but is also scenic with more interstate is take I-49 south to Fort Smith, 71 south to Highway 270 East.
Or Highway 65 to Little Rock and it is only about 25 miles further.
2009 American Eagle 42'
Trailering HD Road Glide and Saab 9.3 or Cadillac Escalade ESV