Stay on 101 all the way across the Golden Gate. There is a a short stretch around Leggett that is slow going, but is fine, no worse than some parts of the Oregon coast. Highway 1 for the most part is not to be done in an RV. Take the TV or toad for excursions to the coast.
Having said that, once you get across the Golden Gate Bridge, take 19th Ave to I-280, then take Highway 1 through Pacifica, Half Moon Bay, Santa Cruz, and on to Monterey. This stretch is perfectly suited for an RV. STOP at Monterey and head back over to 101 to go further south. Do not take 1 past Monterey!
19th Ave is about the easiest and shortest way through the city. Its a large six lane road with plenty of stop lights but its fairly easy, there is no other way except a long detour around or lots of other traffic through the bay area. Plus the coast is beautiful and its an easy drive on Highway 1 at that point, far better than all the freeway traffic!
Enjoy the drive! Tom