Originally Posted by K-Star
Wayne and Ken, you know the roads better than I. But how about:
I-10E -> 36S -> I-69 -> 6 -> I-45
or does that get you too close to Houston???
I think you meant I-59. No, as I posted earlier that is just backtracking to me. Without a toll road pass, my preferred route would be one of two options for quickness. I-10 to I-45S to Galveston, or I-10 to I-610 to I-45S to Galveston. As stated I would avoid the Houston area between 7-9 a.m., and 3-6 p.m.. Most people are at work by 9 a.m. and the traffic lightens up some. The rush hour home is longer because of varying schedules. Even a little after 6 p.m. there can be pockets of heavy traffic. Travelin through Houston between 9 or 10 a.m. and 3 p.m. is the best avoidance of heavy traffic.
If coming from SA and do not want city driving at all, then I-10 to 36S to 1442 over to Alvin. About a 1-2 mile jaunt on 35N to US-6S. US-6S will merge with I-45 at Bayou Vista. Not as much traffic but a little more stop and go.