U.S. 50 through Nevada is an interesting route, and is certainly okay for your rig. As desert country goes, it is a very scenic route. I took that route from Colorado to California several years ago on my motorcycle. U.S. 50 through that part of the U.S. is known as "the lonesomest road in America" for a reason. Towns are scarce and far apart. Plan your trip accordingly.
'99 Diplomat 38A- "High Plains Drifter"
'02 Wrangler Tender