That is such a great trip! I would suggest that you get your map out, and plot your way by going from destination to destination. You do not have to look far to find great stops along the way. You will find many Corps of Engineer & Lake side recreation areas that will be the highlight (s)of your trip.
Do not forget the Land between the Lakes,Natchez Trace, The Smokies,Jim Beam Distilleries, Mobile, Fairhope Ala, Eufala Ala, Just to name a few. Fla campgrounds in the panhandle are the best-all of them are great!
You can't miss with your trip-Have a ball !!