You will have no problems on I-84 from Scranton all the way to Sturbridge, MA. It's the secondary roads you need to be careful of in the east. Some are not only narrow but there are quite a few low underpasses to be aware of. You should not have any trouble on any of the Interstate Highways.
The other thing to be aware of is parkways. In MA, CT and NY the only vehicles allowed on the parkways are cars and motorcycles.
I would also suggest picking up a copy of the
2012 Motor Carriers' Road Atlas. If a highway is highlighted in yellow you will fit.