I drive I-77 through southern WV often in a car. While it's nothing an RV cannot do, it is hilly and curvy and I can't imagine going that way to avoid Cincy (or even Atlanta-like traffic for that matter).
Larry, Beverly & Pat
Pups - Sweetie, Coco, Bodie
2013 Thor Tuscany, 45', Freightliner chassis, Cummins ISL10, towing a Buick Enclave