It's been several years since we did that route while heading over to Montrose. Long, boring, dry road was not very smooth but relatively straight with a few small (very) towns. Altitude went from around 6K or so up to about 8300 or a little better (near midway) then back to around 69 hundred. No mountains but you do drive through some notches between ridges. Road is below average for a lot of Colorado hiways, but you should have no problem with your hookup.
Now 50 to the west is a bit more daunting!
Take a look at Google earth if you want to see some actual road footage