I've driven to Niagra and Toronto a couple times but not in the MH. I cannot remember if there are any "bad" mountains this way, but I would set your GPS for Erie, PA and then when you get near Erie, set it to head for Richmond, VA. This will get you on I-95 south bypassing Baltimore and Washington D.C. Once past Richmond, VA set the GPS for Sarasota.
The general route will be I-90 WEST, I-79 South, I-76 East, I-70 East, I-270 South, I-495 South, I-95 South.
Good luck and enjoy your trip!
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2015 Holiday Rambler Augusta 31M, Ford E-450 Chassis
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