I also did a MapQuest from the same points and it told me going around through Ohio would add approx. 132 miles. I myself have had little experience crossing the border in an auto and no experience in a MH.
From what I have read on other forums it should be no big deal.
I am 52 and so far have had no issues driving at night. Its normally cooler and once you are past the normal commuting hours traffic usually drops off. So yes , it makes a whole lot of sense to get several hours behind you Friday night , pull into a service plaza for some sleep , and go for it in the am.
Speaking of Service Plazas has anyone parked overnight at any of the New York Thruway service plazas ?
As far as my wife driving , she has only driven our 1st MH for a total of 4 miles which was a 24ft Class C. The only thing she has done in the drivers
seat of our current DP is to raise the jacks , start it, and air up. There have been indications recently that she is finally willing to try this spring , we will see.