Hi Gil... you'll love your new toy. I haven't had much chance to play yet because we've been covering >300 miles per day getting from Minnesota to Arizona since I installed it. Just this evening I was able to get the cables routed for a finished installation but still haven't gotten my head into the screens, options, etc.
However, although I can't help you with the Vista question, I do know that it runs fine on my HP Netbook (XP) with Streets & Trips with the GPS Receiver.
Good luck and keep us posted...
Rick, Nancy, Peanut & Lola our Westie Dogs & Bailey the Sheltie.
2007 Itasca Ellipse 40FD