We looked at both and went with the Pilot back in 2004. Our cousin has an MDX, I believe a year or two earlier model. The engine and drivetrain, etc... are all the same on our 2004 Pilot as on the 2 year earlier MDX. Plus, there really is quite a bit more space in the Pilot. We've found it much more comfortable and all around a great car. It tows behind the motorhome just fine, took it all the way back through South Dakota, Yellowstone, etc.. and back. Be carefull though, somewhere along the line, between the 2004 and current models, Honda stopped supporting the idea of flat towing them. I do not know if they actually changed anything, or simply got tired of warranting things when people did it wrong, but either way, the newer models exclude flat towing, at least according to Honda and their owners manual. Good luck!
2008 Newmar Kountry Star 3943
2008 Jeep Rubicon Unlimited