I have had two coach's with one slide and the present with two, both on street side.
I have found its easier when setting up to do all the hook-ups, remove chairs,tables after leveling and before opening the slides.
Would probably do the same if I had four slides.
With two slides on street side the passenger side larger compartments can be arranged with convenience for items you may need also, as cook stove and fun items.
The interior of coach we have has a full wardrobe clothing closets in bedroom, which newer coach's now do not have, with full bath in rear and the living slide extended makes for a cozier atmosphere with half bath at mid coach.
Granted its not a dance floor as with four slides but plenty of room for us old couple.