The scenery on the NTP doesn't really change much. Just a quiet, 50 mph, 2 lane road through the same kind of trees. After about 45 minutes it kinda gets boring.
I'd take I 20 east to I 55, I 55 up to Winona or Grenada, then go east from either to the NTP, then the NTP to Tupalo.
2004 Fleetwood Southwind 32VS W20
ReadyBrute Elite towing a 2017 Ford Edge Sport