I have not on an rv. But with the placement of the xurrent mirrors, getting wiring in and keeping the windows from tearing it up will be a major PITA as it looks like the window and track will be right where you want to put it.
That beingb said, I am sure it is possible but you will probably have a few days of install and fab work to do it.
2021 Grand Design Reflection 303rls
2019 ram 2500 crew cab 6.4l hemi.