Welcome to iRV2.
I'll pass on my experience from 14 years doing Dodge / Cummins repairs (93/07) at a Chrysler /Dodge dealership .
During those years , I dealt with two #53 blocks , one killer dowel pin , and more VP-44 injector pump / lift pump issues than I care to remember. To this day ( 13 years retired )I'll swear, I could pull the required tools from my tool box and change a VP-44 injector pump; on a Dodge P/U; in under flat rate time.
Yes there are any number of the #53 blocks out there , still in service .
I don't know if Cummins ever collected or released info on the failure rate.
Will they ever fail ? Good question.
Even with the failure , external crack along the water jacket , the engine still runs and can be kept cool with cautious eye on the coolant level , so being stranded by the fault isn't really the issue , it's the $$$$ to repair.