I considered the same thing when we had our old 1994 Airstream.
Then I came to my senses and just bought a newer rig!
I'm not sure you could do the swap without beefing up the frame, changing out the steering box and PS pump, and possibly relocating the steering column where it goes through the floor.
It could be done, but not easily.
Happy Glamping, Norman & Elna. 2008 Winnebago Adventurer 38J, W24, dozens of small thirsty ponies. Retired after 40 years wrenching on trucks! 2010 Ford Ranger toad with bicycles or KLR 650 in the back. Easy to spot an RVer, they always walk around with a screwdriver or wrench in one hand!