I had significant vibration issues with my new 2006 Itasca 35U. I see it as important to diagnose and correct vibration problems in the correct sequence. I believe the order of steps below is a good one.
First isolation step was to confirm correct conditions with rims and tire pressures....and front alignment.
Second step was to diagnose status of driveline. I had a bad rear diff gear. WH replaced under warranty through work with WH Service Center. An experienced driveline tech is needed to pin this problem down..if it exists..using tools mentioned here.
www.differentials.com/diagnose.html
Third step was to add the 700 Series Centramatics. A little pricey but it's lifetime balance and a smooth ride saves both tires, shocks and coach electronics and adds great longterm drive day comfort. Adding Centramatics to rear duals versus just steer tires really smoothed out the rear of the coach. Centramatics balance the complete wheel-tire assembly...rotating brake parts etc...not just tire and rim..
www.centramatic.com/howworks.html
Fourth step was to add insulation to the engine compartment hump cover. Both radiated engine and road heat and road-tire noise is reduced by adding insulation here.
Final step was to add Koni FSD shocks to all four wheels.
My rig now is as smooth and quiet in the comparments as most luxury cars..One can actually talk in normal voice to pax while driving. Radio/CD is like listening at home. Driver fatigue is greatly reduced on long drive days.
Good luck..