I've not done mine so I couldn't tell you how difficult it may or may not be.
It seems from a bit of researching that the lower hose in other F53 also attach to the cab heater hoses and a few others.
I'd suggest you get under your rig and take a closer look.
Here is a link to someone else here that was considering replacing the hose on their F-53 a few years ago.
Take a look at the complete assembly of the whole hose.
Price varies between $80 and $120
Good luck
http://www.irv2.com/forums/f23/f53-r...nt-319105.html