I'll add my 2 cents, I always tried to follow Busskipper's rule: be ready the night before you leave, and leave after work Friday. now that I and wife are retired, we try to be ready the night before and leave early the next morning. I have no problem driving hard the first couple days to make miles, so we can spend time at destination, (DW doesn't always agree with me on this). If your wife can drive, that will help with driver fatigue, I always said if I want to just relax, I can do that at home. on vacation- want to see/do things I wouldn't normally get. As to your itinerary, i'd follow the advice given by many here and limit to the Yellowstone/GTNP area. The easiest time I found thru Chicago area was 1-2 am returning from Maine to Nebraska, probably not going to help you much. Did you mention how old the kids were? try to have plenty to keep them busy in the MH on some of the long mile days, more than just videos. Above all, get out and enjoy!
Ted & Arlene
2015 Silverado K2500 crew cab longbed
2015 KZ Durango 1500 295