It is possible!
Just completed a 9490 mile vacation trip with not any time lost for repairs! That doesn't mean there were no nagging little problems but nothing got in the way of our travels. From Florida to a TN Rally, to KY for family to 'Falling Water', Valley Forge, NYC, MA for Family to Salt Lake City and Utah Parks. And then CO and SD plus upper MI peninsula before heading home. All in a 2004 36' Holiday Rambler Vacationer with 50,000 miles pulling a Honda M/C (trike). Mostly stayed in RV campgrounds but at least 7 nights (out of 76) just sitting in parking lots with the Gen running (Love the RV museum in Elkhart - with pond/fountain view right out our windows camping in their parking lot). And for the curious, avg'd 7.4 mpg (gas) even with going to Utah Nat'l Parks and all the mountain climbs including Loveland Pass. And that was with extra 2500 lbs pulling trailer w/ trike. Could have done without the steps acting up (ever try to find a two step stool with no handle to use when steps would not go out - Walmart, HD, Lowes? - or having to carry the dog outside - at midnight - because there were no steps?). And the roads were so rough in places that we lost a motorized shade - driver's side. Just broke the plastic ends that held it to the ceiling! and while driving - not the distraction you want! And of course, all the rough roads kept affecting the slides not wanting to work. I got really good at tapping the relays and slamming the basement doors so they would start working.
But that was it - no lost time for anything major so with 9400 miles trouble free, thoughts turn to a possible trip to Alaska next summer. It is great FUN to see this wonderful country in an RV!
2004 Holiday Rambler Vacationer 36WDD (Workhorse Chassis)
2004 Honda Goldwing w/trike kit
1995 27' Fleetwood Flair (Sold)
US Navy - Vietnam Swiftboat Vet - PCF 102, PCF-62