We drove that section last year as part of an extended trip we took. We were travelling west to east, similar to what you are planning if heading from Thunder Bay to Wawa.
The drive was excellent. In fact, we regarded the stretch across the top of Lake Superior as one of the most enjoyable of our trip. While there were some sections where road work was being done, it was not problematic.
There are plenty of places to gas up so you will have no problems in that regard. There are plenty of places to stay also, but depending on your travel dates you may find them quite busy in the summer months.
We were in a 37 foot rig flat towing a small car and had no problems navigating the drive. We found the roads in good shape and enjoyable. Some of the views of Lake Superior are spectacular.
Our stops were; Nipigon, Marathon and Agawa Bay for the section you referenced.
Enjoy your trip and safe travels.