Yes ; but I wouldn't want to take an RV through there with snow on the road .
There are many sections with steep climbs and descents and the last into Oliver/Osoyoos is a doozy .
When do you plan to travel ?
Have you been on Drive BC to look at the conditions on the web cams?
EDIT: I've driven the route with all four of my 5ers , two different tow vehicles and my coach , good weather, and attention to the grades , it's a very pleasant drive.
99DSDP 3884, Freightliner, XC, CAT 3126B, 300 HP /ALLISON 3060
2000 Caravan toad, Remco & Blue Ox.