We live in the Orlando Metro area. I just completed a round trip from Orlando to Granite City, IL. The above mentioned route of option 1 is good but you could also leave I-24 at Paducah, KY and take US 45 south through Jackson, TN to Tupelo, MS then I-22 from Tupelo to Birmingham, AL then I-65 south to Montgomery, AL. Be aware that there is lots of construction around Birmingham so pick your time wisely. Avoid rush hour traffic if possible. US Highway 45 is four lane all the way with less traffic than Interstate. Lots of choices for fuel, camping, etc. I can give you suggestions for both if needed. Safe travel and enjoy the trip!