An alternative route to consider is US 84 across Mississippi, Louisiana and Texas to Waco. Overall it is a mostly good highway with 65+ MPH speed limits along much of the highway (70-75 in Texas), much of it is 4 laned, and traffic is much lighter than I-10 or I-20, plus you get to see some different scenery. Picking where to make the transition from I-10 to US 84 is up to you, Dothan AL might be a good option, I-10 to US281 to US 84 and on across. If you want to go further west before the cutting over to US 84 then US 49 in Mississippi is another good option, though you might want to shave a few miles off using US98 to get to US84 in Natchez.
2002 Safari Trek 2830 on P32 Chassis with 8.1L