Dog, are you talking about 129 from Gainesville, Ga to Blairsville? (up through Cleveland?) That is not a problem - tractor trailers do it all the time. We have done it numerous times. It is a little curvy going up Blood Mountain to the AT crossing, but doable none-the-less. Down the other side by Vogel and into Blairsville is OK as well, again a few curves is all.
From Blairsville over to Hiawassee it a piece of cake. Same with road from Hiawassee back over to Clayton.
Now 129 in NC across the Dragon is a no-no, but the other part of US 129 is fine. You have just been used to the flat roads and love bugs in Florida too long.