Good Old MO 19 is your typical good hwy through the Ozark Mountains. Yes its very doable, however with that said its not a sit back and enjoy the ride type of road in a MH. If you are not used to driving good two lane mountain roads you will be by the time you finish. Google maps says not quite two hours for your trip, I would plan on 3 or so. If possible go north alittle bit and check out the city of Hermann its well worth the trip.
Please take the road and really enjoy the Ozark Mountains.
2007 Itasca Meridian 36SE
Great Wife & Max the boarder collie
Branson MO the best place to live