Yes, I've done that route.
It will take a couple days longer as you hit lots of small towns but it's a nice trip and cool along the ocean.
2004 Monaco La Palma 36DBD, W22, 8.1, 7.1 MPG
2000 LEXUS RX300 FWD 22MPG 4020 LBS
It's so weird being the same age as old people.