RV wheel bearings are pretty similar to car wheel bearings of old.
I'd suggest using a synthetic grease rated NLGI GC-LB, meaning it meets their highest rating for both wheel bearing and chassis application. Also use new seals. There should be a metal tag on the axle which will give make/model (most likely either Al-Ko or Dexter).
The one thing that is different than cars is that lighter electric brake axles generally do not have self-adjusting electric brakes. Generally, with the axle safely off the ground (jack plus safety stand) and the tire/wheel installed, spin the tire/wheel forward while adjusting the star wheel out until you can't turn the wheel. Then back the star wheel off until you can turn the tire freely, plus about 4 or 5 good bites more on the star wheel...
Unlike manual adjusting drums (really old cars) when properly adjusted you will still hear a skiffing on electric brake axles, which will be the magnet running along the armature surface.
Both Dexter and Al-Ko have very nice downloadable pdf manuals for free.
Under "Service Information" select complete service manual.
http://www.dexteraxle.com/products___literature
And here, just click on "Owner's Manual".
http://www.al-kousa.com/
It is worth it to save both to your hard drive.
As far as frequency, I think both say every 6 months, which I think is a little unrealistic. You would probably never have a problem if you adjusted the brakes a couple times a year, and repacked every two years if you use the trailer frequently. Mine sits up, which I think allows condensation to build up and grease to seperate, so I repack every year.
Good luck, and post back if you have any questions. Sorry about the long post.