Maybe.......Maybe NOT.........some Sprinters have aluminum rims on the front that can not be rotated to the rear. Picture of your fronts would be helpful.
Most have steal rims with hub caps and they can be rotated with no problem.
Some use the theory and practice .............rotate fronts side to side..........leave the rears alone.........replace the fronts when needed and the rear will last a least two or three sets of fronts. This practice also avoids different rolling circumference tires on the duals, this can be come an issue if rotation is delayed way past normal. It also helps when you buy tires, you buy two instead of six.
If you experiencing camber wear ( inside edge) flipping the fronts on the rims helps even out the wear.
Depending on load being carried and camber settings, inside tire wear is a common concern.