It will depend upon your skills, training and abilities. If you plan to travel extensively, that will generally limit your options compared to traveling to a location and take on a temporary position. If you are not nearing retirement, such a plan could have long term negative effects. Future employers are likely to view an unstable work history as unfavorable. If you are performing jobs that do not relate to your long term careers that will put you behind those that are. In some professions, missing a couple of years would mean you are no longer relevant.
If you have strong, desirable skills your options become better. Someone has already mentioned nursing, which is a skill in short supply in many parts of the country. But you don't just proclaim yourself a nurse, you need years of education and training. If you are mechanically inclined, you can find employment many places, but you will be at the bottom of the seniority list and likely get the tasks others don't want to perform. Everyday there are more and more people working from home, and those positions can sometimes be done from the road. But often working from home have requirements that limit traveling. Sometimes the employee needs to go to the office on a weekly basis. Sometimes the internet security, broadband speed and general need for connectivity precludes anything but a static residence. There is no one size fits all job out there.
The workamping type jobs many people advocate are great for stretching a budget and allowing you to travel to amazing places, but they don't put much money in the bank and seldom have even basic benefits. It is almost assuredly not a career path. Our workampers were people at or near retirement who wanted to stretch their finances and/or keep busy while still enjoying traveling. If they had a financial goal it was leaving with as much money as they had when they came using their earnings to pay for necessities and entertainment.